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AccorHotels completes the acquisition of its Paris head office building. Katara Hospitality and AccorHotels to set up an investment fund dedicated to hospitality in Sub-Saharan African countries. AccorHotels acquires Adoria, the European leader in management solutions for corporate and contract catering.
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Par arrêté du Premier ministre en date du 16 septembre , il est nommé Administrateur. Général des Données. Henri Verdier est membre du conseil.
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Metrics details. We hypothesized that this structure, standing at the crossroads of such functions, could ground personal tastes in general, beyond food preferences and aesthetic judgements. Given that dementia with Lewy bodies is characterized by a focal atrophy within the insular cortex from the early stages, this condition provides an opportunity to test such a hypothesis. We developed a questionnaire to assess potential changes in personal tastes, submitted it to a cohort of 23 patients with early-stage dementia with Lewy bodies and compared their questionnaire results to those of 20 age-matched healthy controls.
Our results indicate that the patients presented significant changes in personal tastes compared to the controls, in both food and non-food domains. Moreover, imaging analyses confirmed the involvement of the insular cortex atrophy in the changes in personal tastes using global analysis, and in both food and non-food domains using regional analysis. The insular cortex could be involved through its role in motivational processes by the representation of subjective awareness of bodily states during the phenomenological experience of stimulus appraisal.
However, we also argue that it could support the abstract representations of personal tastes as self-concepts, acutely exemplifying embodied cognition. Finally, the questionnaire on changes in tastes could constitute an interesting tool to help early diagnosis of dementia with Lewy bodies and to assess insular dysfunction more generally. The insular cortex is involved in numerous functions, the complexity of which increases according to the posterior-anterior axis [ 1 ] and is sustained by a specific type of large pyramidal neurons uniquely developed in hominoid primates, the Von Economo neurons [ 2 ].
Insular functions range from primary functions, such as gustation [ 3 , 4 ] and interoception [ 5 , 6 ], to more integrative functions which are based on the formal representations of bodily states, such as self-consciousness [ 1 , 7 ] and social cognition [ 8 , 9 ], together pursuing individual homeostasis. By reverberating emotions through viscerosensory responses, the insula plays a central role in the regulation of emotions [ 10 , 11 , 12 ] and influences decision-making [ 13 , 14 ].
Moreover, beyond its role as a primary gustatory cortex, the insula determines food preference, triggering aversion against harmful food and appetite toward beneficial food according to both survival needs and pleasantness [ 4 ].
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